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136035-10-4

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  • 2-4(1H,3H)-PYRIMIDINEDIONE,1-[5-O-ACETYL-2,3,6-TRIDEOXY-3-(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)-SS-L-RIBO-HEXOFURANOSYL]-5-METHYL-

    Cas No: 136035-10-4

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136035-10-4 Usage

Pyrimidine-2,4-dione core

The central structure of the compound, consisting of a six-membered ring with two carbonyl groups at the 2nd and 4th positions.

Ribofuranose sugar moiety

A five-carbon sugar (ribose) in a furanose form, which is a component of the compound.

Acetyl group

A functional group derived from acetic acid, consisting of a carbonyl group bonded to a methyl group (-COCH3).

Dihydroisoindole group

A fused bicyclic structure consisting of a six-membered benzene ring and a five-membered nitrogen-containing ring (isoindole) with one hydrogen atom added to the isoindole ring.

5-O-acetyl

Indicates that the acetyl group is attached to the 5'-hydroxyl group of the ribofuranose sugar moiety through an ester linkage.

2,3,6-trideoxy

Refers to the absence of hydroxyl groups at the 2nd, 3rd, and 6th carbon positions of the ribofuranose sugar moiety.

3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)

Describes the substitution at the 3rd carbon of the ribofuranose sugar moiety, which is a 1,3-dioxo-1,3-dihydro-2H-isoindole group.

beta-L-ribo-hexofuranosyl

Specifies the stereochemistry and sugar component of the compound, with the ribofuranose sugar in the beta-anomeric configuration and an L-configuration.

5-methyl

Indicates the presence of a methyl group (-CH3) at the 5th position of the pyrimidine-2,4-dione core.

1H,3H

Refers to the hydrogen atoms present in the compound, with 1 hydrogen atom at the 1st position and 3 hydrogen atoms at the 3rd position of the pyrimidine-2,4-dione core.

Biological activities

The compound may exhibit various biological activities, but further research is required to determine its specific effects and potential applications.

Potential applications

Due to its complex structure and possible biological activities, the compound may have potential uses in fields such as pharmaceuticals, biochemistry, or chemical research. However, more investigation is needed to fully understand its properties and potential.

Check Digit Verification of cas no

The CAS Registry Mumber 136035-10-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,0,3 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 136035-10:
(8*1)+(7*3)+(6*6)+(5*0)+(4*3)+(3*5)+(2*1)+(1*0)=94
94 % 10 = 4
So 136035-10-4 is a valid CAS Registry Number.

136035-10-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [(1S)-1-[(2R,3R,5S)-3-(1,3-dioxoisoindol-2-yl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]ethyl] acetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:136035-10-4 SDS

136035-10-4Relevant articles and documents

Synthesis and evaluation of antiviral activity of L-acosamine and L-ristosamine nucleosides of furanose configuration.

Lau,Pedersen,Nielsen

, p. 616 - 620 (2007/10/02)

Mercuric-catalyzed hydrolysis of acetylated L-rhamnal 1 gives an alpha,beta-unsaturated aldehyde 2. 1,4-Addition of DBU-phthalimide salt with concomitant acetyl shift resulted in L-ribo and L-arabino isomers of 5-O-acetyl-2,3,6-trideoxy-3-phthalimido-hexofuranose 3 and 4. After acetylation at the anomeric center, coupling with silylated thymine resulted in three new nucleosides, with L-acosamine and L-ristosamine of furanose configuration as the carbohydrate moiety. The target compounds have been evaluated for their antiviral activity against HIV and HSV-1.

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