1360468-67-2Relevant academic research and scientific papers
Synthesis and antimicrobial studies of 1-methyl-2-dimethylaminoethyl- substituted benzimidazolium salts and N-heterocyclic carbene-silver complexes
Yigit, Beyhan,Goek, Yetkn,Oezdemir, Ilknur,Guenal, Selami
experimental part, p. 371 - 379 (2012/05/31)
The synthesis and antimicrobial studies of 1-methyl-2-dimethylaminoethyl- substituted carbene precursors and silver complexes are reported. The carbene precursors (1a-d) have been prepared from 1-methyl-2-dimethylaminoethyl- substituted benzimidazole and various alkyl halides. The silver-NHC complexes (2a-d) were synthesized from the benzimidazolium salts and Ag2O in dichloromethane at room temperature. The new compounds were characterized by 1H NMR, 13C NMR, FT-IR, and elemental analyses. The new carbene precursors and Ag-complexes were tested for their invitro antimicrobial activity against a variety of Gram-positive and Gram-negative bacteria, as well as for their antifungal activities against Candida albicans and Candida tropicalis. Copyright
