1360600-40-3Relevant academic research and scientific papers
The direct asymmetric alkylation of α-amino aldehydes with 3-indolylmethanols by enamine catalysis
Guo, Zhi-Lei,Xue, Jia-Hui,Fu, Li-Na,Zhang, Shun-En,Guo, Qi-Xiang
supporting information, p. 6472 - 6475 (2015/01/16)
This work describes an efficient α-alkylation reaction of α-amino aldehydes with 3-indolylmethanols. In the promotion of catalyst 3f, the target products were obtained in high yields (up to 99%), good diastereoselectivities (up to 88:12), and excellent en
