1360617-52-2

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 504-02-9 1,3-cylohexanedione 
• 87748-33-2 methyl 3-carbomethoxy-3-(4'-methylphenyl)amino-2-propenoate 
• 106-49-0 p-toluidine 
• 762-42-5 dimethyl acetylenedicarboxylate 

Relevant academic research and scientific papers

Selective synthesis of fused 1,4-and 1,2-dihydropyridines by domino reactions of arylamines, acetylenedicarboxylate, aldehydes, and cyclic 1,3-diketones

A practical procedure for the preparation of fused 1,4-dihydropyridines was developed through the domino four-component reactions of arylamines, acetylenedicarboxylate, aromatic aldehydes, and cyclic 1,3-diketones in acetic acid. Unusual fused 1,2-dihydropyridines can also be efficiently prepared by controlling the reaction conditions.