136062-33-4

Upstream product

• 540-63-6 ethane-1,2-dithiol 
• 579-07-7 1-Phenylpropane-1,2-dione 

Downstream Products

• 136062-36-7 (2-Methyl-[1,3]dithiolan-2-yl)-phenyl-methanol 
• 211739-96-7 2-(1-hydroxy-1-phenylpropyl)-2-methyl-1,3-dithiolane 
• 35756-13-9 2-phenyl-3-methyl-5,6-dihydro-1,4-dithiin 

Relevant academic research and scientific papers

Synthesis of 2,3-dihydro-1,4-dithiins and 2-alkylidene-1,4-dithianes by 1,2-sulfur migration in 2-(1-hydroxyalkyl)-1,3-dithiolanes

2,3-Dihydro-1,4-dithiins and the isomeric 2-alkylidene-1,4-dithianes were synthesized from 1,2-diketones and alkyl pyruvates by kinetically controlled ring expansion of 2-(1-hydroxyalkyl)-1,3-dithiolanes with p-toluenesulfonyl chloride in pyridine. In addition, 2,3-dihydro-1,4-dithiins, the thermodynamic products, were formed exclusively by using p-toluenesulfonic acid in refluxing benzene. The 2-alkylidene-1,4-dithianes were readily isomerised to the corresponding 2,3-dihydro-1,4-dithiins. Similarly, 2,3-dimethyl-6,7-dihydro-5H-1,4-dithiepine and (+)-2-methylene-3-methyl-1,4-diethiepane were obtained from 2-[(S)-1-hydroxyethyl]-2-methyl-1,3-dithiane.