1360626-52-3Relevant academic research and scientific papers
Catalytic asymmetric synthesis of aromatic spiroketals by spinphox/iridium(I)-catalyzed hydrogenation and spiroketalization of α,α′-Bis(2-hydroxyarylidene) ketones
Wang, Xiaoming,Han, Zhaobin,Wang, Zheng,Ding, Kuiling
, p. 936 - 940 (2012/03/08)
From spiro to spiro: An iridium(I) complex with a spiral P,N ligand (SpinPhox) is highly efficient in the catalytic asymmetric hydrogenation of α,α′-bis(2-hydroxyarylidene) ketones to afford the corresponding aromatic spiroketals in high yields with excellent diastereo- and enantioselectivities (see scheme). The complex plays a dual role in the reaction, acting as catalyst for both the hydrogenation of C=C bonds and the subsequent spiroketalization of bisphenolic ketones. Copyright
