1360744-46-2Relevant academic research and scientific papers
Synthesis of 2′-O-guanidinopropyl-modified nucleoside phosphoramidites and their incorporation into siRNAs targeting hepatitis B virus
Brzezinska, Jolanta,D'Onofrio, Jennifer,Buff, Maximilian C.R.,Hean, Justin,Ely, Abdullah,Marimani, Musa,Arbuthnot, Patrick,Engels, Joachim W.
, p. 1594 - 1606 (2012)
Synthetic RNAi activators have shown considerable potential for therapeutic application to silencing of pathology-causing genes. Typically these exogenous RNAi activators comprise duplex RNA of approximately 21 bp with 2 nt overhangs at the 3′ ends. To im
