1360874-40-3

Upstream product

• 1360874-39-0 9-(3-O-benzoyl-2-O-phenoxythiocarbonyl-5-O-trityl-β-D-ribofuranosyl)-6-chloropurine 
• 1005-56-7 phenylcarbonochloridothioate 
• 234436-48-7 9-[3-O-benzoyl-5-O-(triphenylmethyl)-β-D-ribofuranosyl]-6-chloro-9H-purine 

Downstream Products

• 1360874-41-4 [6-⁽¹⁵⁾N]-3'-O-benzoyl-5'-O-trityl-2'-deoxyadenosine 
• 1360874-42-5 [6-⁽¹⁵⁾N]-5'-O-trityl-2'-deoxyadenosine 
• 1360874-43-6 [6-⁽¹⁵⁾N]-3'-O-benzoyl-2'-deoxyadenosine 

Relevant academic research and scientific papers

First synthesis of [6-15N]-cladribine using ribonucleoside as a starting material

We have synthesized two types of [6-15N]-deoxyadenosine analogs: [6-15N]-2'-deoxyadenosine (1) and [6-15N]-2-chloro-2'-deoxyadenosine ([6-15N]-cladribine, 2), which utilized the readily available ribonucleosides inosine and guanosine, respectively, via 3'-benzoyl-5'-trityl- (or tert-butyldimethylsilyl)-substituted intermediates (6, 15).