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Rhodium-catalyzed asymmetric [2+2+2] cyclization of 1,6-enynes and aldehydes
Ishida, Mana,Shibata, Yu,Noguchi, Keiichi,Tanaka, Ken
, p. 12578 - 12581 (2011)
Asymmetric catalysis: The rhodium-catalyzed asymmetric [2+2+2] cyclization of 1,6-enynes and aldehydes was achieved by using a cationic rhodium(I)/(R)-binap complex as a catalyst (see scheme; cod=1,5-cyclooctadiene). Coordination of the substrate heteroatom to the cationic rhodium plays an important role in this cyclization reaction.
