1361022-26-5Relevant academic research and scientific papers
Mukaiyama-Michael vinylogous additions to nitroalkenes under solvent-free conditions
Scettri, Arrigo,Villano, Rosaria,Manzo, Patrizia,Acocella, Maria Rosaria
experimental part, p. 47 - 53 (2012/03/22)
The first Mukaiyama-Michael vinylogous reaction of a dioxinone-derived silyl ether to nitroalkenes is reported. The conjugate addition is performed in absence of any catalyst under solvent-free conditions, proceeding with satisfactory efficiency with variously substituted nitroalkenes. Moreover, the first organocatalyzed Mukaiyama-Michael vinylogous reaction of trimethylsilyloxyfuran to nitroalkenes is described.The reaction is promoted by Bronsted acids under solvent-free conditions, taking place in moderate to good yield with variously substituted nitroalkenes..
