1361026-55-2

Upstream product

• 1234573-87-5 3,6-anhydro-7-O-benzoyl-5-O-benzyl-2-deoxy-7-C-phenyl-D-glycero-D-ido-heptono-1,4-lactone 
• 1361026-56-3 3,6-anhydro-7-O-benzoyl-5-O-benzyl-2-deoxy-7-C-phenyl-D-glycero-L-ido-heptono-1,4-lactone 
• 899436-70-5 5-O-benzoyl-3-O-benzyl-1,2-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose 
• 1457973-40-8 3-O-benzoyl-3-O-benzyl-1,2-O-isopropylidene-5-C-phenyl-β-L-ido-pentofuranose 
• 20715-20-2 3-O-benzyl-1,2-O-isopropylidene-5-C-phenyl-α-D-xylo-pent-5-ulo-furanose 
• 18439-43-5 3-O-benzyl-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentafuranose 
• 65462-15-9 3-O-benzyl-1,2-O-isopropylidene-β-L-arabino-pentodialdo-1,4-furanose 
• 18685-18-2 3-O-benzyl-1,2-5,6-O-diisopropylidene-α-D-glucofuranose 
• 18439-42-4 3-O-benzyl-1,2-O-isopropylidene-5-C-phenyl-α-L-ido-pentofuranose 

Downstream Products

• 1457973-59-9 C₂₀H₂₀O₄ 

Relevant academic research and scientific papers

Heteroannelated and 7-deoxygenated goniofufurone mimics with antitumour activity: Design, synthesis and preliminary SAR studies

Cytotoxic (+)-goniofufurone mimic such as benzoxepane 2 was preferentially formed after the treatment of 7-O-benzoyl-5-O-benzyl (+)-goniofufurone derivative 6 with titanium(IV) fluoride. However, the corresponding 7-epimer 5 (derivative of 7-epi-goniofufu

Novel goniofufurone and 7-epi-goniofufurone mimics from an unexpected titanium-mediated displacement process

Treatment of 7-O-benzoyl-5-O-benzyl derivatives of (+)-goniofufurone or 7-epi-(+)-goniofufurone with titanium(IV) chloride or titanium(IV) bromide gave 7-chloro and 7-bromo-7-deoxy-goniofufurone mimics as the main reaction products along with minor amounts of the corresponding C-7 epimers. An unexpected cyclized product, benzoxepane 8 was isolated in some cases.