1361029-51-7Relevant academic research and scientific papers
One-Pot Michael Addition/Radical Cyclization Reaction of N -Acryloyl Indoles
Irwin, Lauren C.,Kerr, Michael A.
, p. 2859 - 2864 (2017)
From N -acryloyl indoles, ten examples of 1,2-annulated indole products were generated in a one-pot procedure via a Michael addition and radical cyclization mediated by Mn(OAc) 3.
Aerobic palladium(II)-catalyzed 5-endo-trig cyclization: An entry into the diastereoselective C-2 alkenylation of indoles with tri- and tetrasubstituted double bonds
Kandukuri, Sandeep R.,Schiffner, Julia A.,Oestreich, Martin
supporting information; experimental part, p. 1265 - 1269 (2012/03/08)
The endo trick: An endo ring closure onto the trigonal β carbon atom of α,β-unsaturated acceptors that are tethered to the indole nitrogen atom followed by amide cleavage enables the diastereoselective C-2 alkenylation of indoles with fully substituted double bonds. The carboxy group functions as a synthetically useful temporary tether (see scheme). Copyright
