1361030-48-9 Usage
General Description
LDC1267 is a chemical compound that acts as a selective inhibitor of the enzyme autotaxin, which is involved in lipid metabolism and the production of lysophosphatidic acid (LPA). LPA is a bioactive lipid that has been implicated in a variety of biological processes, including cell proliferation, migration, and inflammation. By inhibiting autotaxin, LDC1267 has the potential to modulate LPA levels and thereby impact these biological processes. Research has shown that LDC1267 may have therapeutic potential in the treatment of diseases such as fibrotic disorders, cancer, and inflammatory conditions. Additionally, LDC1267 has demonstrated promising results in preclinical studies, suggesting that it could be a valuable tool for further investigating the role of autotaxin and LPA in disease pathogenesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1361030-48-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,1,0,3 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1361030-48:
(9*1)+(8*3)+(7*6)+(6*1)+(5*0)+(4*3)+(3*0)+(2*4)+(1*8)=109
109 % 10 = 9
So 1361030-48-9 is a valid CAS Registry Number.
1361030-48-9Relevant articles and documents
PHARMACEUTICALLY ACTIVE COMPOUNDS AS AXL INHIBITORS
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Page/Page column 89, (2012/03/26)
The present invention relates to 1-nitrogen-heterocyclic-2-carboxamides of general formula (I): and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the treatment and/or prevention of Axl receptor tyrosine kinase subfamily induced disorders, including cancer and primary tumor metastases, and pharmaceutical compositions containing at least one of said 1-nitrogen-heterocyclic-2-carboxamide derivatives and/or pharmaceutically acceptable salts thereof.
