1361061-39-3Relevant academic research and scientific papers
First- and second-generation practical syntheses of chroman-4-one derivative: A key intermediate for the preparation of SERT/5-HT1A dual inhibitors
Nishida, Tomoaki,Yoshinaga, Hidefumi,Toyoda, Tomohiro,Toshima, Minoru
experimental part, p. 625 - 634 (2012/07/03)
Two approaches to large-scale synthesis of the key intermediate 9, a precursor of novel dual inhibitors of SERT/5-HT1A receptor, are described. These two approaches each feature a mild and efficient method for construction of the chroman-4-one
