1361119-22-3Relevant academic research and scientific papers
Quaternary centres as a tool for modulating foldamer conformation
Galeazzi, Roberta,Martelli, Gianluca,Mazzanti, Andrea,Orena, Mario,Rinaldi, Samuele
, p. 12564 - 12568 (2011)
Centre refold: (3R,4S,1′S)-4-Amino-1-(1′-(4-methoxyphenyl) ethyl)-3-methyl-5-oxopyrrolidine-3-carboxylic acid (AMMOPC) gives a foldamer with an 8-helix conformation. When it was inserted in the 12-helix foldamer of (3R,4S,1′S)-4-amino-1-(1′-(4-methoxyphenyl)ethyl) -5-oxo-pyrrolidine-3-carboxylic acid (AMOPC), it locally induced formation of an 8-helix conformation (see figure).
