1361131-75-0Relevant academic research and scientific papers
Asymmetric construction of quaternary stereocenters: Synthesis of enantiopure amino acid-based tricyclic α,β-enones through an ipso-Friedel-Crafts/Michael addition cascade
Rodriguez-Solla, Humberto,Concellon, Carmen,Tuya, Paula,Garcia-Granda, Santiago,Diaz, M. Rosario
experimental part, p. 295 - 300 (2012/04/04)
An efficient reaction of the (2R,1′S)- or (2S,1′S)-N,N-bis(p- methoxybenzyl)-2-(1-aminoalkyl)epoxides, derived from α-amino acids, with boron trifluoride-phosphoric acid complex is described. This process affords highly elaborated enantiopure tricyclic α,β-enones in high yields, through an ipso-Friedel-Crafts/Michael addition cascade. Copyright
