136114-05-1

Basic information

• Product Name: N-[((1R,2S,5R)-8-phenylmenthoxy)carbonyl]-1-(4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 136114-05-1
• Molecular Weight: 601.783
• Mol File: 136114-05-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[((1R,2S,5R)-8-phenylmenthoxy)carbonyl]-1-(4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: N-[((1R,2S,5R)-8-phenylmenthoxy)carbonyl]-1-(4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(136114-05-1)
• EPA Substance Registry System: N-[((1R,2S,5R)-8-phenylmenthoxy)carbonyl]-1-(4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(136114-05-1)

Safety Data

• Hazardous Substances Data: 136114-05-1(Hazardous Substances Data)

Upstream product

• 136114-04-0 N-[((1R,2S,5R)-8-phenylmenthoxyl)carbonyl]-2-(3,4-dimethoxyphenyl)ethylamine 
• 159730-37-7 1-(3,4-dimethoxyphenyl)-2-methoxyethylene 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 126378-43-6 (1R,2S,5R)-(-)-8-phenylmenthyl chloroformate 
• 136114-02-8 (E)-1,2-dimethoxy-4-(2-methoxyethenyl)benzene 

Downstream Products

• 65253-04-5 (-)-8-phenylmenthol 
• 2688-77-9 (S)-laudanosine 
• 85-63-2 (R)-laudanosine 

Relevant articles and documents

Chiral auxiliary mediated pictet-spengler reactions: Asymmetric syntheses of (-)-laudanosine, (+)-glaucine and (-)-xylopinine

Cyclohexyl-based chiral auxiliaries can be used effectively in an asymmetric Pictet-Spengler synthesis of tetrahydroisoquinoline, aporphine and protoberbine alkaloids. Using this strategy, concise asymmetric syntheses of (-)-laudanosine, (+)-glaucine and (+)- xylopinine have been accomplished.