1361143-10-3Relevant academic research and scientific papers
The dynamic kinetic resolution of azlactones with thiol nucleophiles catalyzed by arylated, deoxygenated cinchona alkaloids
Rodriguez-Docampo, Zaida,Quigley, Cormac,Tallon, Sean,Connon, Stephen J.
, p. 2407 - 2414 (2012/05/05)
A significant improvement of the available organocatalytic methods (in terms of product substrate scope and product enantiomeric excess) for the generation of enantioenriched α-amino acid thioesters via the dynamic kinetic resolution of azlactones is reported. C-9 arylated cinchona alkaloid catalysts have been found to be considerably superior to other bifunctional alkaloid catalysts as the promoters of this asymmetric process.
