136121-27-2

Basic information

• Product Name: 1-(1-Chlorovinyl)-4-t-butyl-1-cyclohexanol
• Synonyms: 1-(1-Chlorovinyl)-4-t-butyl-1-cyclohexanol
• CAS NO: 136121-27-2
• Molecular Weight: 216.751
• Mol File: 136121-27-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1-Chlorovinyl)-4-t-butyl-1-cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Chlorovinyl)-4-t-butyl-1-cyclohexanol(136121-27-2)
• EPA Substance Registry System: 1-(1-Chlorovinyl)-4-t-butyl-1-cyclohexanol(136121-27-2)

Safety Data

• Hazardous Substances Data: 136121-27-2(Hazardous Substances Data)

Upstream product

• 98-53-3 4-tercbutyl-cyclohexanone 
• 159763-13-0 1-<1-chloro-1-(p-tolylsulfinyl)ethyl>-4-tert-butyl-1-cyclohexanol 

Downstream Products

• 136121-33-0 1-<3-Hydroxy-3-(3-methoxyphenyl)-1-propynyl>-4-t-butyl-1-cyclohexanol 
• 20325-03-5 4-(1,1-dimethylethyl)-1-ethynylcyclohexanol 
• 136121-31-8 1-<2-(1-Hydroxycyclohexyl)ethyl>-4-t-butyl-1-cyclohexanol 

Relevant articles and documents

1-Chloroalkyl p-Tolyl Sulfoxides as Acetylide Anion Equivalent: A Novel Synthesis Including Asymmetric Synthesis of Propargylic Alcohols from Carbonyl Compounds

Addition of the carbanion of 1-chloroalkyl p-tolyl sulfoxide to carbonyl compounds gave the adducts, which were heated in refluxing toluene or xylene to give vinyl chlorides in high overall yield.Dehydrochlorination of the vinyl chlorides with excess n-BuLi afforded propargylic alcohols in high yields.Asymmetric synthesis of both enantiomers of the propargylic alcohols was realized using optically active 1-chloroalkyl p-tolyl sulfoxide and aldehyde.