1361214-40-5

Upstream product

• 81069-39-8 (E)-ethyl 3-(3-iodophenyl)acrylate 
• 696-41-3 m-iodobenzaldehyde 
• 745078-70-0 (E)-3-(3-iodophenyl)prop-2-en-1-ol 

Downstream Products

• 1361214-41-6 C₂₅H₂₉IN₂O₃ 
• 1361214-44-9 (R)-tert-butyl 3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate 
• 1361214-47-2 (R)-3-((2R,3S)-2-((E)-3-iodostyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoic acid 
• 1354566-03-2 AVN 576 

Relevant academic research and scientific papers

Metal- and Acid-Free Methyl Triflate Catalyzed Meyer-Schuster Rearrangement

A novel metal- and acid-free preparation of synthetically useful α,β-unsaturated carbonyl compounds from propargyl alcohols has been realized. This Meyer-Schuster rearrangement process is effectively catalyzed by methyl triflate (20 mol%) to prepare a broad scope of conjugated E -enals and E -enones generally in good to excellent yields (up to 90%). This reaction procedure operates under mild conditions (70 °C), in air, with short reaction times (1 h). Moreover, a carbocation intermediate trapped by the solvent 2,2,2-trifluoroethanol was isolated during this transformation.

Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging

SRX246 is a potent, highly selective human vasopressin V1a antagonist that crosses the blood-brain barrier in rats. CNS penetration makes SRX246 an ideal candidate for potential radiolabeling and use in visualization and characterization of the role of th