Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide that plays a crucial role in multiple physiological processes in the body. It is involved in the regulation of hormone secretion, neuronal survival, neuroprotection, neurotransmission, immune response, and circadian rhythm modulation. PACAP also exhibits vasodilatory and neuroprotective effects, making it a potential therapeutic target for various neurological disorders. Furthermore, it impacts the development and function of the central nervous system, highlighting its significance in brain development and function. Overall, PACAP is a multifunctional signaling molecule with far-reaching effects on various physiological processes in the body.
136134-68-4
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Basic information
- Product Name: PITUITARY ADENYLATE CYCLASE ACTIVATING
- Synonyms: PITUITARY ADENYLATE CYCLASE ACTIVATING;pacap-6-27;pituitary adenylate cyclase activating polypeptide amide fragment 6-27;Pituitary Adenylate Cyclase Activating Polypeptide-27 (6-27) (huMan, chicken, Mouse, ovine, porcine, rat)
- CAS NO:136134-68-4
- Molecular Formula: C121H193N33O31S
- Molecular Weight: 2638.09462
- EINECS: N/A
- Product Categories: N/A
- Mol File: 136134-68-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: PITUITARY ADENYLATE CYCLASE ACTIVATING(CAS DataBase Reference)
- NIST Chemistry Reference: PITUITARY ADENYLATE CYCLASE ACTIVATING(136134-68-4)
- EPA Substance Registry System: PITUITARY ADENYLATE CYCLASE ACTIVATING(136134-68-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 136134-68-4(Hazardous Substances Data)
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136134-68-4 Usage
Uses
Used in Pharmaceutical Industry:PACAP is used as a therapeutic target for neurological disorders due to its neuroprotective and vasodilatory effects. Its potential applications include the treatment of neurodegenerative diseases, cerebrovascular disorders, and traumatic brain injuries.
Used in Research and Development:
PACAP is utilized in research for understanding the molecular mechanisms underlying its diverse physiological functions. It serves as a valuable tool for studying the regulation of hormone secretion, neuronal survival, neurotransmission, immune response, and circadian rhythm modulation.
Used in Drug Delivery Systems:
PACAP can be incorporated into drug delivery systems to enhance its therapeutic efficacy and bioavailability. Novel drug delivery systems, such as nanoparticles or hydrogels, can be developed to encapsulate PACAP, allowing for controlled release and targeted delivery to specific tissues or cells.
Used in Diagnostic Applications:
PACAP can be employed as a biomarker for the diagnosis and monitoring of neurological disorders. Its levels in biological samples, such as cerebrospinal fluid or blood, can provide valuable information about the progression and severity of the disease.
Used in Neuroregeneration and Repair:
PACAP has the potential to promote neurogenesis and neural repair, making it a valuable tool in the development of regenerative therapies for neurological disorders. Its neuroprotective and neurotrophic properties can support the survival and regeneration of damaged neurons, contributing to functional recovery.
Check Digit Verification of cas no
The CAS Registry Mumber 136134-68-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,1,3 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.Calculate Digit Verification of CAS Registry Number 136134-68:
(8*1)+(7*3)+(6*6)+(5*1)+(4*3)+(3*4)+(2*6)+(1*8)=114
114 % 10 = 4
So 136134-68-4 is a valid CAS Registry Number.
136134-68-4Upstream product
136134-68-4Downstream Products
136134-68-4Related news
Full Length ArticleProtective effects of PITUITARY ADENYLATE CYCLASE ACTIVATING (cas 136134-68-4) polypeptide against neurotoxic agents09/02/2019
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide highly expressed in the central and peripheral nervous system, where it exerts several neuromodulatory functions and is an important trophic and protective factor. PACAP has been shown to activate several protective pat...detailed
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PITUITARY ADENYLATE CYCLASE ACTIVATING
