1361344-09-3

Upstream product

• 83863-33-6 5-iodo-o-toluidine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1361344-10-6 2,2'-((4-methoxyphenylazanediyl)bis(2-methyl-5,1-phenylene))diisoindoline-1,3-dione 
• 1361344-11-7 C₃₇H₂₅N₃⁽¹⁵⁾NO₆⁽¹⁺⁾ 
• 1361344-12-8 C₂₁H₂₁N₃⁽¹⁵⁾NO⁽¹⁺⁾ 

Relevant academic research and scientific papers

Manipulating reduction potentials in an artificial safranin cofactor

Safranines hold great promise as artificial flavin-like electron transfer cofactors with tunable properties. We report the design and chemical synthesis of the p-methoxy derivative of safranine O using a new synthetic route based on the Ulmann condensation. Spectroelectrochemical comparison of the purified parent safranine and this derivative demonstrates that the modification increases its two-electron reduction potential by 125 mV, or 5.75 kcal/mol. This modification also causes redshifts in the absorbance and fluorescence spectra of the cofactor, suggesting that it may find future utility in arrayed sensor applications.