1361386-73-3

Upstream product

• 1361386-72-2 5-tert-butyl-2-((3,3-dimethylureido)methyl)benzoic acid 
• 1361386-71-1 3-(4-tert-butylbenzyl)-1,1-dimethylurea 
• 7364-19-4 4-ethyl-tert-butylbenzene 

Downstream Products

• 1231890-99-5 2-(3-bromo-2-methylphenyl)-6-tert-butylisoindolin-1-one 
• 1231892-49-1 6-tert-butyl-2-(2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)isoindolin-1-one 

Relevant academic research and scientific papers

PYRIDAZINONES, METHOD OF MAKING, AND METHOD OF USE THEREOF

Pyridazinone compounds of Formula (I) including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula (I) for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.