1361387-76-9

Upstream product

• 1361387-50-9 (E)-1-(methoxyimino)-4-methyl-1-phenylpentan-3-one 
• 13988-65-3 4-methyl-1-phenyl-pentane-1,3-dione 

Downstream Products

• 1361386-93-7 methyl 2-isopropyl-3-phenyl-2H-azirine-2-carboxylate 
• 1361388-10-4 1-(2-methoxy-3-phenyl-2H-azirin-2-yl)-2-methylpropan-1-one 

Relevant academic research and scientific papers

The synthesis of pyrroles and oxazoles based on gold α-imino carbene complexes

Cationic gold complexes of α-oximimino carbenes have been identified to react with weak nucleophiles including enol ethers and nitriles. These findings allowed us to develop the highly efficient synthesis of pyrroles and oxazoles.

Synthesis of unsymmetrical pyrazines based on ?±-diazo oxime ethers

Synthesis of unsymmetrically substituted pyrazines has been a challenge. The reactivity of ?±-imino carbenoids derived from ?±-diazo oxime ethers has been exploited for pyrazine synthesis, in which the reaction of ?±-diazo oxime ethers with 2H-azirines provides highly substituted pyrazines in good to excellent yields.

METHOD FOR PREPARING 2H-AZIRINE CARBOXYLIC ESTERS

The invention relates to a method for preparing 2H-azirine carboxylic esters. More specifically, the invention relates to a method for preparing 2H-azirine carboxylic esters starting from α-diazo-β-keto oxime ethers in the presence of a rhodium (II)-based

Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers

An efficient rhodium-catalyzed synthesis of 2H-azirines and pyrroles has been developed. Novel rearrangement of α-oximino ketenes derived from α-diazo oxime ethers provides 2H-azirines bearing quaternary centers and allows for subsequent rearrangement to highly substituted pyrroles in excellent yields.