1361391-30-1Relevant academic research and scientific papers
Intramolecular oxidative diamination and aminohydroxylation of olefins under metal-free conditions
Kim, Hyun Jin,Cho, Seung Hwan,Chang, Sukbok
, p. 1424 - 1427 (2012)
A metal-free procedure that is simple to operate and convenient to handle was developed for the facile intramolecular oxidative diamination of olefins using an iodobenzene diacetate oxidant and a halide additive to furnish bisindolines at room temperature. The present reaction is featured by mild conditions, a broad substrate scope, and excellent functional group tolerance. The same protocol was successfully extended to the aminohydroxylation.
