1361405-12-0Relevant academic research and scientific papers
Pd-catalyzed direct arylation of polyfluoroarenes on water under mild conditions using PPh3 ligand
Chen, Fei,Min, Qiao-Qiao,Zhang, Xingang
, p. 2992 - 2998 (2012/05/04)
We report a Pd-catalyzed direct arylation of polyfluoroarenes with aryl iodides. The advantages of this reaction are its high reaction efficiency, excellent functional group compatibility, mild reaction conditions (70 °C), inexpensive PPh3 ligand, and use of pure water as reaction medium. The usefulness of this reaction has also been demonstrated by rapid preparation of highly functionalized polyfluoroarenes via iterative Pd-catalyzed C-H bond functionalization.
