136152-05-1

Basic information

• Product Name: (E)-(2S,3R)-1-Benzyloxymethoxy-2,4,6-trimethyl-hept-4-en-3-ol
• CAS NO: 136152-05-1
• Molecular Weight: 292.419
• Mol File: 136152-05-1.mol

Chemical Properties

• CAS DataBase Reference: (E)-(2S,3R)-1-Benzyloxymethoxy-2,4,6-trimethyl-hept-4-en-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(2S,3R)-1-Benzyloxymethoxy-2,4,6-trimethyl-hept-4-en-3-ol(136152-05-1)
• EPA Substance Registry System: (E)-(2S,3R)-1-Benzyloxymethoxy-2,4,6-trimethyl-hept-4-en-3-ol(136152-05-1)

Safety Data

• Hazardous Substances Data: 136152-05-1(Hazardous Substances Data)

Upstream product

• 116021-11-5 (S)-(+)-(benzyloxy)methyl 3-<(benzyloxy)methoxy>-2-methylpropionate 
• 102518-03-6 (R)-(+)-3-<(benzyloxy)methoxy>-2-methylpropanol 
• 3587-60-8 Benzyloxymethyl chloride 

Downstream Products

• 136152-11-9 Triphenyl-((E)-(2R,3S)-2,4,6-trimethyl-3-trimethylsilanyloxy-hept-4-enyl)-phosphonium; iodide 
• 136152-09-5 Toluene-4-sulfonic acid (E)-(2S,3S)-3-hydroxy-2,4,6-trimethyl-hept-4-enyl ester 

Relevant articles and documents

Synthesis of an avermectin-nemadectin hybrid

The Wittig condensation of (2R,3R,4E)-2,6-dimethyl-3-trimethylsilyloxy-4- heptenyltriphenylphosphorylidene with aldehyde 1 produced the desired cis olefin 11 in 45% yield. Treatment of this intermediate with pyridinium tosylate in methanol effected spiroketalization and desilylation with hydrogen fluoride-pyridine in THF afforded the avermectin-nemadectin hybrid 2.