1361539-95-8Relevant academic research and scientific papers
Nuclease activity via self-activation and anticancer activity of a mononuclear copper(II) complex: Novel role of the tertiary butyl group in the ligand frame
Ghosh, Kaushik,Kumar, Pramod,Mohan, Varun,Singh, Udai P.,Kasiri, Sahba,Mandal, Subhrangsu S.
, p. 3343 - 3345 (2012)
The copper complex [Cu(tBuPhimp)(Cl)] (1) derived from tridentate ligand tBuPhimpH having N2O donors was synthesized, and its molecular structure was determined. A phenoxyl radical complex was generated in solution at room temperature using Ce(IV). The nuclease and anticancer activities of 1 were investigated. The roles of the tert-butyl group and singlet oxygen in the DNA cleavage activity were also discussed.
