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(5S,6S)-((2S,3R)-2-methyl-1-(tosyloxy)hex-5-en-3-yl) 5-(tert-butyldimethylsilyloxy)-6-methylnon-8-enoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1361550-95-9

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1361550-95-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1361550-95-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,1,5,5 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1361550-95:
(9*1)+(8*3)+(7*6)+(6*1)+(5*5)+(4*5)+(3*0)+(2*9)+(1*5)=149
149 % 10 = 9
So 1361550-95-9 is a valid CAS Registry Number.

1361550-95-9Relevant academic research and scientific papers

A diverted total synthesis of mycolactone analogues: An insight into buruli ulcer toxins

Chany, Anne-Caroline,Casarotto, Virginie,Schmitt, Marjorie,Tarnus, Celine,Guenin-Mace, Laure,Demangel, Caroline,Mirguet, Olivier,Eustache, Jacques,Blanchard, Nicolas

, p. 14413 - 14419 (2011)

Mycolactones are complex macrolides responsible for a severe necrotizing skin disease called Buruli ulcer. Deciphering their functional interactions is of fundamental importance for the understanding, and ultimately, the control of this devastating mycobacterial infection. We report herein a diverted total synthesis approach of mycolactones analogues and provide the first insights into their structure-activity relationship based on cytopathic assays on L929 fibroblasts. The lowest concentration inducing a cytopathic effect was determined for selected analogues, allowing a clear picture to emerge by comparison with the natural toxins.

STRUCTURAL VARIANTS OF MYCOLACTONES FOR USE IN MODULATING INFLAMMATION, IMMUNITY AND PAIN

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, (2013/06/05)

The present invention is related to variants of mycolactones of formula (I), processes for the preparation thereof, pharmaceutical compositions thereof and their use in modulating inflammation, immunity and pain. Y-O-W (I), wherein Y and W are as defined in claim 1.

Structural variants of mycolactones for use in modulating inflammation, immunity and pain

-

, (2013/06/05)

The present invention is related to variants of mycolactones of formula (I), processes for the preparation thereof, pharmaceutical compositions thereof and their use in modulating inflammation, immunity and pain. ???????? Y-O-W?????(I) wherein Y and W are as defined in claim 1.

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