1361552-42-2Relevant academic research and scientific papers
The first examples of seco-prezizaane-type norsesquiterpenoids with neurotrophic activity from Illicium jiadifengpi
Kubo, Miwa,Kobayashi, Kana,Huang, Jian-Mei,Harada, Kenichi,Fukuyama, Yoshiyasu
, p. 1231 - 1235 (2012)
Two seco-prezizaane-type sesquiterpenoids (2R)-hydroxy-norneomajucin (1) and jiadifenone (2) that represent the first examples of nor-type were isolated from the methanol extract of the pericarps of Illicium jiadifengpi. Their structures and the absolute configuration of 1 were established by the analysis of spectroscopic data and chemical conversion of (2S)-hydroxyneomajucin to 1, respectively. In addition, compound 1 exhibited neurotrophic activity to significantly promote neurite outgrowth in the primary cultured rat cortical neurons at concentrations ranging from 1 to 10 μmol L-1.
