136175-22-9

Basic information

• Product Name: 2-tert-butyl-2-phenyl-1-(4-tolylsulfonyl)aziridine
• Synonyms: 2-tert-butyl-2-phenyl-1-(4-tolylsulfonyl)aziridine
• CAS NO: 136175-22-9
• Molecular Weight: 329.463
• Mol File: 136175-22-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-tert-butyl-2-phenyl-1-(4-tolylsulfonyl)aziridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butyl-2-phenyl-1-(4-tolylsulfonyl)aziridine(136175-22-9)
• EPA Substance Registry System: 2-tert-butyl-2-phenyl-1-(4-tolylsulfonyl)aziridine(136175-22-9)

Safety Data

• Hazardous Substances Data: 136175-22-9(Hazardous Substances Data)

Upstream product

• 938-16-9 2,2-dimethylpropiophenone 
• 65855-34-7 2-tert-butyl-2-phenyl-aziridine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 65855-34-7 2-tert-butyl-2-phenyl-aziridine 
• 86429-26-7 (+/-)-3,3-dimethyl-2-phenylbutanal 
• 769-57-3 α,β,β-trimethylstyrene 
• 70-55-3 toluene-4-sulfonamide 
• 726-18-1 4,4'-dianisylmethane 
• 1576-37-0 N-benzyl-p-toluenesulfonamide 
• 107524-67-4 2,3-diphenyl-2-methylbutane 
• 4381-14-0 9,9'-bixanthene 
• 136175-27-4 2-tert-butyl-3-(9-xanthenyl)-2-phenylaziridine 
• 136201-62-2 9-<3,3-dimethyl-2-phenyl-2-(4-tolylsulfonamido)butyl>xanthene 
• 90-47-1 xanth-9-one 
• 136175-25-2 9-<3,3-dimethyl-2-phenyl-2-(4-tolylsulfonamido)butyl>-9,10-dihydroanthracene 

Relevant articles and documents

Electron-deficient olefin ligands enable generation of quaternary carbons by Ni-catalyzed cross-coupling

A Ni-catalyzed Negishi cross-coupling with 1,1-disubstituted styrenyl aziridines has been developed. This method delivers valuable β-substituted phenethylamines via a challenging reductive elimination that affords a quaternary carbon. A novel electron-deficient olefin ligand, Fro-DO, proved crucial for achieving high rates and chemoselectivity for C-C bond formation over β-H elimination. This ligand is easy to access, is stable, and presents a modular framework for reaction discovery and optimization. We expect that these attributes, combined with the fact that the ligands impart distinct electronic properties to a metal, will support the invention of new transformations not previously possible using established ligands.