136192-81-9Relevant academic research and scientific papers
Studies of the new herbicide KIH-6127. Part III. Synthesis and structure-activity studies of analogues of KIH-6127 against barnyard grass (Echinochloa oryzicola)
Tamaru,Masuyama,Sato,Takabe,Inoue,Hanai
, p. 76 - 84 (1997)
The previously evaluated prototype, methyl 6-acetyl-2-[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate, was modified by the introduction of an oximino group. Further extensive synthetic modifications were then made to the 6-alkyl moiety (R1), the est
Method for synthesizing herbicide pyriminobac-methyl in paddy field
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Paragraph 0015; 0042-0043; 0057-0059; 0063; 0077-0079; 0083, (2021/02/24)
The invention belongs to the field of fine chemical engineering, and particularly relates to a preparation method of herbicide pyriminobac-methyl for a paddy fields. The preparation method comprises the following steps: synthesizing 3-hydroxy phthalic anhydride by using 3-chlorophthalic anhydride as a new raw material, protecting carbonyl by using diethyl malonate, hydrolyzing to obtain 2-acetyl-6-hydroxy benzoic acid, and esterifying to obtain 2-acetyl-6-hydroxy methyl benzoate; then carrying out imidization reaction with methoxyamine hydrochloride to obtain 2-hydroxy-6-(1-methoxy iminoethyl-methyl)-benzoate, and finally, condensing with 2-tosyl-4, 6-dimethoxypyrimidine to obtain pyriminobac-methyl. In the process of preparing pyriminobac-methyl, high-risk reagents such as n-butyllithiumare avoided, a large amount of wastewater generated by diazotization is avoided, the income is increased, and the environment is protected.
