1361938-46-6

Upstream product

• 102-96-5 (2-nitroethenyl)benzene 
• 13176-46-0 4-bromoethyl acetoacetate 
• 638-07-3 ethyl (2-chloroaceto)acetate 
• 1384456-74-9 C₁₄H₁₆ClNO₅ 

Downstream Products

• 1361938-67-1 4-hydroxy-3-(2-nitro-1-phenylethyl)furan-2(5H)-one 
• 1361938-68-2 (E)-3-(1,2-dihydroxyethylidene)-4-phenylpyrrolidin-2-one 
• 1384456-81-8 C₁₂H₁₁NO₅ 

Relevant academic research and scientific papers

Synthesis of chiral tetronic acid derivatives via organocatalytic conjugate addition of ethyl 4-chloro-3-oxobutanoate to nitroalkenes

Asymmetric conjugate addition of ethyl 4-chloro-3-oxobutanoate to nitroalkenes and subsequent intramolecular cyclization had been developed. This one-pot reaction provided tetronic acid derivatives in good yields and with excellent enantioselectivities. 6

From the Feist-Bénary reaction to organocatalytic domino Michael-alkylation reactions: Asymmetric synthesis of 3(2H)-furanones

It all adds up! A modified Feist-Bénary reaction employing a domino Michael-alkylation sequence was designed for the enantioselective synthesis of 3(2H)-furanones. L-Threonine-derived tertiary amine/thiourea catalysts were prepared for the first time; such catalysts promoted the designed domino Michael-alkylation reactions in a highly enantioselective manner (see scheme). Copyright