136202-05-6Relevant academic research and scientific papers
Manganese(III)-mediated direct phosphonylation of arenes
Xu, Wei,Zou, Jian-Ping,Zhang, Wei
supporting information; experimental part, p. 2639 - 2643 (2010/06/16)
Manganese (III)-promoted direct phosphonylation of mono- and disubstituted arenes with dialkylphosphite afforded regioselective dialkylphosphonates in good yields. The reactions can apply to arenes bearing electron-donating groups and electron-withdrawing
Synthesis, resolution and applications of 3,3′-bis(RO)-MeO-BIPHEP derivatives
Gorobets, Evgueni,Sun, Guang-Ri,Wheatley, Bronwen M.M.,Parvez, Masood,Keay, Brian A.
, p. 3597 - 3601 (2007/10/03)
A series of optically pure 3,3′-bis(RO)-MeO-BIPHEP derivatives are prepared and used in palladium catalyzed asymmetric transformations. The phosphine oxide of (±)-5 is prepared in four steps from p-methoxyphenol and resolved using the novel resolving reag
Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions
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, (2008/06/13)
3,3′-Substituted chiral biaryl phosphine and phosphinite ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes are useful as catalysts in asymmetric reactions, such as, hydrogenation, hy
Selective Ortho Lithiation of (2,5-Dimethoxyphenyl)diphenylphosphine Oxide and Trapping of the Resulting Aryllithium with Electrophiles
Brown, John M.,Woodward, Simon
, p. 6803 - 6809 (2007/10/02)
The title compound undergoes predominant 6-lithiation, ortho to the methoxy and phosphinoyl groups, on reaction with t-BuLi in THF under conditions of thermodynamic control at low temperature.The organolithium compound is stable at least to 0 deg C and can be trapped by a range of electrophiles to give the corresponding tetrasubstituted (diphenylphosphinoyl)arenes in moderate to good yield.The iodide formed by this sequence undergoes Ullman coupling to the diphenyl, which exhibits a novel restricted rotation phenomenon, in good yield under mild conditions. (2,5-Dimethoxyphenyl)diphenylphosphine sulfide lithiates exclusively at the 4-position under the same conditions, whilst the corresponding phosphine is unreactive.
