1362023-07-1Relevant articles and documents
Probe sialidase substrate specificity using chemoenzymatically synthesized sialosides containing C9-modified sialic acid
Khedri, Zahra,Muthana, Musleh M.,Li, Yanhong,Muthana, Saddam M.,Yu, Hai,Cao, Hongzhi,Chen, Xi
supporting information; experimental part, p. 3357 - 3359 (2012/05/04)
A library of α2-3- and α2-6-linked sialyl galactosides containing C9-modified sialic acids was synthesized from C6-modified mannose derivatives using an efficient one-pot three-enzyme system. These sialosides were used in a high-throughput sialidase substrate specificity assay to elucidate the importance of C9-OH in sialidase recognition. The Royal Society of Chemistry 2012.