136203-48-0Relevant academic research and scientific papers
Synthesis of chlorine-containing angucycline BE-23254 and its analogs
Mal, Dipakranjan,Dey, Satyajit
, p. 9589 - 9602 (2007/10/03)
The total synthesis of BE-23254, an unusual angucycline antibiotic is reported. This is achieved by adopting a Hauser annulation and a DDQ-promoted aromatization as the key steps. The strategy has been generalized for the synthesis of several analogs of the target molecule. A regioselective preparation of chlorine-containing phenols is also described.
Total synthesis of BE-23254, a chlorinated angucycline antibiotic
Dey, Satyajit,Mal, Dipakranjan
, p. 5483 - 5486 (2007/10/03)
The first synthesis of BE-23254, an unusual angucycline antibiotic, is reported. It involves regioselective condensation of naphthalenone 4 and chlorine-containing isobenzofuranone 16 as the key step.
