136205-66-8 Usage
Physical state
Colorless liquid The compound appears as a colorless liquid, which means it does not have a visible color and flows like a liquid.
Usage in pharmaceuticals and agricultural chemicals
Production 2,3-Aziridinedicarboxylic acid, dimethyl ester, cis-(9CI) is used in the manufacturing process of pharmaceuticals and agricultural chemicals, indicating its importance in these industries.
Use as a reagent in organic synthesis
Facilitates chemical reactions 2,3-Aziridinedicarboxylic acid, dimethyl ester, cis-(9CI) serves as a reagent in organic synthesis, meaning it helps facilitate chemical reactions and is an essential component in the synthesis process.
Building block for functional molecules
Preparation of various molecules The compound is also used as a building block for the preparation of various functional molecules, highlighting its versatility and importance in chemical research and development.
Hazardous chemical classification
Handle and store according to safety regulations As a hazardous chemical, 2,3-Aziridinedicarboxylic acid, dimethyl ester, cis-(9CI) must be handled and stored in accordance with safety regulations to ensure the safety of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 136205-66-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,2,0 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 136205-66:
(8*1)+(7*3)+(6*6)+(5*2)+(4*0)+(3*5)+(2*6)+(1*6)=108
108 % 10 = 8
So 136205-66-8 is a valid CAS Registry Number.
136205-66-8Relevant articles and documents
ONE STEP SYNTHESIS OF AZIRIDINES BY THE MICHAEL TYPE ADDITION OF FREE SULFIMIDES
Furukawa, Naomichi,Yoshimura, Toshiaki,Ohtsu, Masami,Akasaka, Takeshi,Oae, Shigeru
, p. 73 - 80 (2007/10/02)
The Michael type additions of diphenyl N-unsubstituted sulfimide (free sulfimide) to various electrophilic olefins were carried out.The reaction with cis- and trans-dibenzoylethylene, dimethylfumarate, dimethylmaleate, benzalacetophenone and benzalacetone gave mainly the corresponding trans-2-acylaziridines and trans-enaminoketones.However, phenyl vinyl sulfone or acrylonitrile afforded not the corresponding aziridine but diphenyl-N-2-cyano or N-2-phenylsulfonylethylsulfimide, a simple Michael adduct.When optically active (+)-(R)-o-methoxyphenylphenyl free sulfimide was treated with such an α,β-unsaturated carbonyl compound as benzalacetophenone, an optically active 2-acylaziridine, i.e., (-)-trans-2-benzoyl-3-phenylaziridine was obtained in ca 30percent optical purity and its absolute configuration was assigned as (2R,3S) upon chemical transformation to the configurationally known 2-phenyl-2-benzoylamino-1-ethanol or by comparing its CD spectrum with that of (1R,2R)-1-phenyl-2-benzoyl-cyclopropane.Meanwhile, (-)-(S)-o-methoxyphenylphenyl free sulfimide was found to react with benzalacetophenone to afford (+)-trans-2-benzoyl-3-phenylaziridine of 25percent optical purity.Effects of solvent and temperature on both the distribution of the products ratio and the optical yield were examined.
