136258-79-2Relevant academic research and scientific papers
Dihydronaphthyridine potassium channel openers
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, (2008/06/13)
Compounds of formula I are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
β-Keto-δ-valerolactone: Synthesis and use as methylvinylketone anion equivalent in michael additions
D'Angelo, Jean,Gomez-Pardo, Domingo
, p. 3063 - 3066 (2007/10/02)
β-Keto-δ-valerolactone 11 was prepared from 3-butyn-l-ol 6 in 5 steps (50 % overall yield). This lactone was added to Michael acceptors 13, 17, 19 and 25, giving adducts 14, 18, 20 and 26 respectively.
