136264-87-4

Upstream product

• 136374-64-6 (8S,8aR)-3,8-Dimethyl-2,5,6,7,8,8a-hexahydro-1H-azulen-4-one 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 136490-25-0 3-(3,3-(dimethylenedioxy)butyl)-4-methylcycloheptan-1-one 
• 136490-23-8 6-(3,3-(dimethylenedioxy)butyl)-5-methyl-1-(trimethylsiloxy)bicyclo<3.2.0>heptan-6-ol 
• 136490-24-9 3-(3,3-(dimethylenedioxy)butyl)-4-methylcyclohept-3-en-1-one 
• 136490-28-3 4-Methyl-3-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-cycloheptanol 
• 125302-45-6 (1R,5S)-5-Methyl-1-trimethylsilanyloxy-bicyclo[3.2.0]heptan-6-one 
• 70147-72-7 1,4-dimethyl-2,3,3a,4,5,6-hexahydroazulen-8(7H)-one 
• 136264-81-8 (4S,6S)-3-<2-(ethoxycarbonyl)ethyl>-4-methyl-6-trimethylsilylcycloheptanone 
• 136264-82-9 (3S,4S)-3-<2-(ethoxycarbonyl)ethyl>-4-methylcycloheptanone 
• 136264-85-2 3-((1S,2S)-2-Methyl-6-oxo-cyclohept-4-enyl)-propionic acid ethyl ester 
• 136264-90-9 3-((1S,2S)-2-Methyl-6-oxo-cycloheptyl)-propionic acid 
• 136264-83-0 (3S,4S)-4-Methyl-3-(3-oxo-butyl)-cycloheptanone 
• 136264-80-7 (4S,6S)-4-methyl-6-trimethylsilyl-2-cycloheptenone 

Relevant academic research and scientific papers

Total Synthesis of (+/-)-Clavukerin A: A New Trinorguaiane Sesquiterpene. Biomimetic Synthesis of (+/-)-Clavularin A from (+/-)-Clavukerin A

(+/-)-Clavukerin A, 2,8-dimethylbicyclodeca-5,7-diene, was first synthesized utilizing thermal cycloaddition and two carbon ring expansion reactions as key elements. (+/-)-Clavukerin A was transformed, via photooxidation mimicking the biogene

Total Synthesis of Clavukerin A and Its Epimer

Enantioselective synthesis of clavukerin A and its epimer was carried out.By the comparison of the spectral data and specific rotations of synthesized and natural ones, two trinorsesquiterpens isolated from Clavulia and Cespitularia species are confirmed