1362688-12-7Relevant academic research and scientific papers
Unification of anion relay chemistry with the Takeda and Hiyama cross-coupling reactions: Identification of an effective silicon-based transfer agent
Smith III, Amos B.,Hoye, Adam T.,Martinez-Solorio, Dionicio,Kim, Won-Suk,Tong, Rongbiao
supporting information; experimental part, p. 4533 - 4536 (2012/04/23)
The unification of Anion Relay Chemistry (ARC) with the Takeda and Hiyama palladium-mediated cross-coupling processes to provide aryl-aryl, alkenyl-aryl, and alkenyl-alkenyl coupled products by exploiting a common silicon-based transfer agent has been achieved. These results provide a practical solution for intermolecular cross-coupling of organolithium reagents without the problematic lithium-halogen exchange and/or undesired homocoupling that has kept organolithium cross-couplings from achieving the same level of utility asother palladium-mediated methods (e.g., Suzuki organoboron, Negishi organozinc, Stille organotin, Kumada organomagnesium, etc.).
