136269-33-5Relevant academic research and scientific papers
POSSIBLE REACTION PATHWAYS FOR THE FORMATION OF 3-CHLORO-4-(DICHLOROMETHYL)-5-HYDROXY-2(5H)-FURANONE (MX).
Langvik, Vivi-Ann,Hormi, Osmo
, p. 1111 - 1118 (1994)
Three compounds, 3,4,5-trimethoxybenzaldehyde (I), 1-dichloromethyl-3,4,5-trimethoxy-benzene (II) and 3,4,5-trimethoxyphenylacetic acid (III) were treated with aqueous chlorine at pH 2. Aqueous chlorination of the three compounds increased the formation of MX (3-chloro-4-dichloromethyl-5(2H)-hydroxyfuranone) and E-MX (E 2-chloro-3-dichloromethyl-4-oxo-butenoic acid) in the order I>II>III. By 1H-NMR spectroscopy and gas chromatography it was shown that II hydrolizes readily to I in water. It is known that III is converted to II in chlorination reactions. We suggest that the (formed) aldehyde group remains intact during the formation of MX and E-MX from these three compounds. They could thus form MX and E-MX, via similar mechanisms. This suggested mechanism may also occur when phenolic precursor structures present in humic material are treated with chlorine in the process of drinking water production.
Process for opening cyclopropane rings
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, (2008/06/13)
Process for ring opening compounds of the formula STR1 in which R1 is heteroaryl or aryl, R2 is a leaving group, R3, R4, R5 and R6 are independently selected from hydrogen, alkyl, aralkyl,
