136282-52-5Relevant academic research and scientific papers
The First Mechanism-Based Inactivators for Angiotensin-Converting Enzyme
Ghosh, Soumitra S.,Said-Nejad, Odile,Roestamadji, Juliatiek,Mobashery, Shahriar
, p. 4175 - 4179 (2007/10/02)
The first example of mechanism-based inactivation of angiotensin-converting enzyme (ACE) is described for N--L-phenylalanine (compound 1).It is proposed that an ACE-mediated deprotonation of 1 unmasks a ketenimine intermedi
