1362850-83-6

Upstream product

• 1362850-82-5 2-methylpropane-2(S)-sulfinic acid [(R)-1-(8-chloro-2-phenylquinolin-3-yl)-2,2,2-trifluoroethyl]amide 
• 1362850-81-4 2-methylpropane-2(S)-sulfinic acid N-(8-chloro-2-phenylquinolin-3-yl)meth-(E)-ylidene-amide 
• 1362850-80-3 8-chloro-2-phenylquinoline-3-carbaldehyde 
• 144918-96-7 2,8-dichloroquinoline-3-carbaldehyde 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1362850-22-3 N-[(R)-1-(8-chloro-2-phenylquinolin-3-yl)-2,2,2-trifluoroethyl]pyrido[3,2-d]pyrimidin-4-ylamine 

Relevant academic research and scientific papers

QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS

A series of quinoline and quinoxaline derivatives comprising a fluorinated ethyl side-chain, being selective inhibitors of P13 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.