136286-29-8

Basic information

• Product Name: N-(1-methyl-1,2-diphenylethyl)glycinamide di[(2E)-but-2-enedioate]
• CAS NO: 136286-29-8
• Molecular Formula: C₂₅H₂₈N₂O₉
• Molecular Weight: 500.4978
• Mol File: 136286-29-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 466.4°C at 760 mmHg
• Flash Point: 235.9°C
• Vapor Pressure: 7.09E-09mmHg at 25°C
• CAS DataBase Reference: N-(1-methyl-1,2-diphenylethyl)glycinamide di[(2E)-but-2-enedioate](CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-methyl-1,2-diphenylethyl)glycinamide di[(2E)-but-2-enedioate](136286-29-8)
• EPA Substance Registry System: N-(1-methyl-1,2-diphenylethyl)glycinamide di[(2E)-but-2-enedioate](136286-29-8)

Safety Data

• Hazardous Substances Data: 136286-29-8(Hazardous Substances Data)

Upstream product

• 118910-28-4 1,2 diphenyl 2 propylamine 

Relevant articles and documents

Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties

There is provided a method of treatment of neurological disorders, such as epilepsy, stroke and cerebral ischaemia, which comprises the administration of a compound of Formula I: STR1 wherein, Ar1 and Ar2, which may be the same or different, independently represent phenyl or phenyl substituted by one or more of amino, nitro, halogen, hydroxy, C1 to 6 alkoxy, C1 to 6 alkyl or cyano; R1 represents hydrogen, C1 to 6 alkyl, C1 to 6 alkoxycarbonyl; R2 represents hydrogen or COCH2 NH2 ; R3 represents hydrogen or C1 to 6 alkyl; in addition, when R2 represents hydrogen either one or both of Ar1 and Ar2 may also represent 2-, 3- or 4-pyridinyl and R1 may also represent trihalomethyl; or a pharmaceutically acceptable salt thereof. Some of the compounds of formula I are novel, and these are also provided, together with pharmaceutical compositions containing the novel compounds.