136290-47-6

Usage

Uses

Used in Pharmaceutical Industry:
ANTHRANILIC ACID, N-BOC-4-CHLORO is used as a reagent for the synthesis of various pharmaceutical compounds. Its role in the production of bioactive molecules makes it a valuable component in drug development.
Used in Chemical Synthesis:
ANTHRANILIC ACID, N-BOC-4-CHLORO is used as an intermediate compound in the synthesis of complex molecules with potential applications in various fields, including medicine and biotechnology. Its versatility in chemical reactions contributes to the creation of new and innovative compounds.

InChI:InChI=1/C12H14ClNO4/c1-12(2,3)18-11(17)14-9-6-7(13)4-5-8(9)10(15)16/h4-6H,1-3H3,(H,14,17)(H,15,16)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 89-77-0 2-Amino-4-chlorobenzoic acid 

Downstream Products

• 1246921-14-1 N-(2-{3-[2-fluoro-3-(trifluoromethyl)phenyl]-8-methoxy-4-oxocinnolin-1(4H)-yl}ethyl)methanesulphonamide 
• 1246779-66-7 N-(3-[3-[2-Fluoro-3-(trifluoromethyl)phenyl]-8-methoxy-4-oxocinnolin-1(4H)-yl]propyl)methanesulphonamide 
• 1246779-65-6 7-Chloro-3-[2-chloro-3-(trifluoromethyl)phenyl]-1-(5,5,5-trifluoropentyl)-4a,8a-dihydrocinnolin-4(1H)-one 
• 1246779-50-9 3-[2-Fluoro-3-(trifluoromethyl)phenyl]-8-methoxy-1-pentylcinnolin-4(1H)-one 
• 90417-27-9 8-methoxy-1H-cinnolin-4-one 
• 33844-20-1 3-bromo-8-methoxy-1H-cinnolin-4-one 
• 1204652-87-8 3-bromo-7-chloro-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one 

Relevant academic research and scientific papers

SUBSTITUTED 1-ALKYLCINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION OF SAME

The subject of the present invention is compounds corresponding to the formula (I) in which: X represents a divalent (C2-C5)alkylene radical which is unsubstituted or substituted one or more times by an Alk group; R1 represents a phenyl, a naphthyl, a pyridyl, a 1-benzothienyl or a 1,3-benzodioxolyl; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group or else a group chosen from —S-Alk, —SO-Alk, —SO2-Alk, —CO—N(R4)-Alk, —N(R4)SO2-Alk, —N(R4)CO-Alk, —N(R4)SO2—N(Alk)2; R3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 represents a hydrogen atom or a (C1-C4)alkyl; Alk represents an unsubstituted or substituted (C1-C4)alkyl. Preparation process and therapeutic application.

SUBSTITUTED 1-BENZYL-CINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF

The present invention is related to novel substituted 1-benzylcinnolin-4(1H)-one derivatives having affinity for cannabinoid CB2 receptors, their preparation and their therapeutic application.

Synthesis of a quinolone library from ynones

A library of 72 quinolones was synthesized from substituted anthranilic acids, using ynone intermediates. These masked β-dicarbonyl synthons allowed cyclization under milder conditions than previously reported quinolone syntheses.