1363130-63-5Relevant academic research and scientific papers
Endoperoxide synthesis by photocatalytic aerobic [2 + 2 + 2] cycloadditions
Parrish, Jonathan D.,Ischay, Michael A.,Lu, Zhan,Guo, Song,Peters, Noel R.,Yoon, Tehshik P.
, p. 1640 - 1643 (2012/05/04)
Structurally novel endoperoxides can be sythesized by the photocatalytic cyclotrimerization of bis(styrene) substrates with molecular oxygen. The optimal catalyst for this process is Ru(bpz)32+, which is a markedly more efficient catalyst for these photooxygention reactions than conventional organic photosensitizers. The 1,2-dioxolane products are amenable to synthetic manipulation and can be easily processed to 1,4-diols and γ-hydroxyketones. An initial screen of the biological activity of these compounds reveals promising inhibition of cancer cell growth.
