13633-30-2Relevant academic research and scientific papers
Organozinc reagents in DMSO solvent: Remarkable promotion of S N2′ reaction for allene synthesis
Kobayashi, Koji,Naka, Hiroshi,Wheatley, Andrew E. H.,Kondo, Yoshinori
supporting information; experimental part, p. 3375 - 3377 (2009/05/30)
(Chemical Equation Presented) The SN2′ reaction of propragyl mesylates with organozinc reagents was dramatically improved in DMSO solvent, and the stereoselective conversion of chiral substrates was successfully achieved using LiCl-free diorgan
A CONVENIENT SYNTHESIS OF ALLENES BY THE REACTION OF PROPARGYL ALCOHOLS WITH GRIGNARD REAGENTS USING 1-CHLORO-2-METHYL-N,N-TETRAMETHYLENEPROPENYLAMINE
Fujisawa, Tamotsu,Iida, Sachio,Sato, Toshio
, p. 4007 - 4010 (2007/10/02)
1-Chloro-2-methyl-N,N-tetramethylenepropenylamine was found to be an efficient condensation reagent for the regioselective coupling reaction of propargyl alcohols with Grignard reagents to give allenes in good yields with high chemo- and enantioselectivities.The utility of the reaction was demonstrated in the stereocontrolled synthesis of methyl (E)-2,4,5-tetradecatrienoate, the pheromone of the male dried bean beetle.
