1363334-16-0Relevant academic research and scientific papers
Molybdenum trioxide catalyzed oxidative cross-dehydrogenative coupling of benzylic sp3 C-H bonds: Synthesis of α-aminophosphonates under aerobic conditions
Alagiri, Kaliyamoorthy,Devadig, Pradeep,Prabhu, Kandikere R.
, p. 1456 - 1459 (2012)
Molybdenum trioxide (MoO3) catalyzed efficient oxidative cross-dehydrogenative-coupling (CDC) method for C-H functionalization of N-aryl tetrahydroisoquinolines has been explored. This user-friendly method of synthesizing α-aminophosphonates employs 1.1 equiv of dialkyl-H- phosphonate under aerobic condition. Formation of new C-P bonds from unfunctionalized starting materials under environmentally benign conditions provides an excellent avenue for the synthesis of biologically active α-aminophosphonates.
CDC reactions of N-aryl tetrahydroisoquinolines using catalytic amounts of DDQ: C-H activation under aerobic conditions
Alagiri, Kaliyamoorthy,Devadig, Pradeep,Prabhu, Kandikere R.
supporting information; experimental part, p. 5160 - 5164 (2012/05/20)
An oxidative cross-dehydrogenative coupling (CDC) reaction for the formation of C-C and C-P bonds is disclosed using a catalytic amount of DDQ (10 mol %) under aerobic conditions (see scheme). This unprecedented environmentally benign strategy of using AI
