1363334-18-2Relevant academic research and scientific papers
Molybdenum trioxide catalyzed oxidative cross-dehydrogenative coupling of benzylic sp3 C-H bonds: Synthesis of α-aminophosphonates under aerobic conditions
Alagiri, Kaliyamoorthy,Devadig, Pradeep,Prabhu, Kandikere R.
, p. 1456 - 1459 (2012/04/04)
Molybdenum trioxide (MoO3) catalyzed efficient oxidative cross-dehydrogenative-coupling (CDC) method for C-H functionalization of N-aryl tetrahydroisoquinolines has been explored. This user-friendly method of synthesizing α-aminophosphonates employs 1.1 equiv of dialkyl-H- phosphonate under aerobic condition. Formation of new C-P bonds from unfunctionalized starting materials under environmentally benign conditions provides an excellent avenue for the synthesis of biologically active α-aminophosphonates.
