Tert-butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting the epidermal growth factor receptor (EGFR). Its unique chemical structure allows for the development of potent inhibitors, making it a valuable asset in the field of medicinal chemistry.
1363381-22-9
Post Buying Request-
-
Basic information
- Product Name: tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate
- Synonyms: tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate;2-Azaspiro[3.5]nonane-2-carboxylic acid, 7-oxo-, 1,1-dimethylethyl ester
- CAS NO:1363381-22-9
- Molecular Formula: C13H21NO3
- Molecular Weight: 239.31074
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1363381-22-9.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: 348.6±42.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.12±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- PKA: -0.84±0.20(Predicted)
- CAS DataBase Reference: tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate(CAS DataBase Reference)
- NIST Chemistry Reference: tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate(1363381-22-9)
- EPA Substance Registry System: tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate(1363381-22-9)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1363381-22-9(Hazardous Substances Data)
1363381-22-9 Suppliers
Recommended suppliers
1363381-22-9 Usage
Uses
Used in Pharmaceutical Industry:Tert-butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate is used as a key intermediate for the preparation of diaminopyrimidines, which are known as EGFR inhibitors. These inhibitors play a crucial role in the development of targeted therapies for various types of cancer, as they help in modulating the activity of the epidermal growth factor receptor, a protein often associated with tumor growth and progression.
The compound's application in the pharmaceutical industry is primarily due to its ability to facilitate the synthesis of EGFR inhibitors, which are essential in the treatment of cancer. By providing a stable and efficient route to these therapeutic agents, Tert-butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate contributes to the advancement of cancer research and the development of novel treatment options.
Check Digit Verification of cas no
The CAS Registry Mumber 1363381-22-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,3,3,8 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1363381-22:
(9*1)+(8*3)+(7*6)+(6*3)+(5*3)+(4*8)+(3*1)+(2*2)+(1*2)=149
149 % 10 = 9
So 1363381-22-9 is a valid CAS Registry Number.
1363381-22-9Upstream product
1363381-22-9Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 1363381-22-9
tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate
